SecureBio Detection

Senior infrastructure engineer; [senior] software engineer (high-performance pipelines)

hn · location n/a

scored

Jose has exceptional full-stack and infrastructure engineering credentials with proven ability to architect and scale production systems handling millions of users and complex data pipelines. His experience building real-time systems at scale (WebRTC, concurrent sessions, 99.9% reliability), designing data platforms (Trino, S3, Postgres, Redis), and owning infrastructure/DevOps across AWS and GCP directly matches the senior infrastructure engineer and high-performance pipeline roles. The main gap is lack of direct bioinformatics or scientific computing domain experience, and no explicit mention of HPC optimization, GPU computing, or large-scale genomic data processing.

Hook: Your experience architecting data platforms and real-time pipelines at scale, plus your proven track record owning cloud infrastructure and infrastructure-as-code, makes you a strong fit for our senior infrastructure and high-performance pipeline engineering roles.

Missing: bioinformatics domain knowledge, genomic data processing experience, HPC optimization and GPU computing, scientific computing workflows, experience with genome sequencing or metagenomic analysis tools

original posting ↗

Posting

SecureBio Detection | Senior infrastructure engineer; [senior] software engineer (high-performance pipelines)
Cambridge, MA, USA (metro Boston) | ONSITE strongly preferred; REMOTE (US east coast) possible for exceptional candidates

SecureBio is a nonprofit working to protect the world from catastrophic pandemics. We operate the world’s largest metagenomic biosurveillance network, which performs daily sequencing of wastewater samples and nasal swabs to screen for emerging pathogens. Our computational team develops detection pipelines responsible for rapid processing of deep sequencing data in order to flag potential threats.

I'm the hiring manager for two roles:

- Senior infrastructure engineer, to own cloud infra, devops, CI/CD, AWS security, etc. https://securebio.org/careers/2026-cloud-infra-engineer/

- [Senior] software engineer focused on high performance data pipelines. https://securebio.org/careers/2026-software-engineer-pipelines/

Prior experience with biology or bioinformatics is not required. If you're interested, please apply via the relevant job posting. Feel free to drop me a line with questions; email is in my profile.

https://securebio.org/careers/